Abstract: In order to effectively detect the failure of network system, a novel detection algorithm FDMBFO (Failure Detection algorithm based on Fuzzy Neural Network) is proposed by fuzzy neural network. In this algorithm, the failure detection method and the minimum deviation optimization model have proposed by feature information entropy, and Input Layer, Fuzzy Layer, Fuzzy Rule Layer and Ambiguity Layer have designed. Then, the algorithm processes is presented. Finally, an experiment with simulation platform was conducted to study the key factors of FDD-FNN. Compared to performance of other algorithm, the results show that FDD-FNN has better adaptability.